Scientist, Translational PK/PD Modeling – Spring House, PA

Job title: Scientist, Translational PK/PD Modeling – Spring House, PA

Company: Johnson & Johnson

Job description: Janssen Research & Development, a member of the Pharmaceutical Companies of Johnson & Johnson, is recruiting for a Scientist in Translational PK/PD Modeling, located in Spring House, PA.

Janssen Research & Development, L.L.C. develops treatments that improve the health and lifestyles of people worldwide. t areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, hematology, metabolic disorders, immunologic disorders, and reproductive medicine.

The Translational PK/PD (pharmacokinetic/pharmacodynamic) Modeling Scientist uses mathematical modeling techniques to support discovery programs across multiple therapeutic areas. The Scientist will be a key member of cross-disciplinary discovery project teams and will be responsible for developing quantitative dose- and exposure-response relationships in preclinical studies and for predicting efficacious human doses. The Scientist will evaluate a broad range of in vitro and in vivo data to develop integrated mathematical models characterizing the effects of drug candidates and support the advancement of the most promising molecules to investigational new drug (IND) filings and human studies. The Scientist will highlight key uncertainties associated with the existing data and modeling and collaborate with other team members to design additional studies that will provide necessary data to improve the modeling and predictions. Mathematical modeling approaches and software used will include physiologically-based pharmacokinetic modeling (e.g., Simcyp, GastroPlus) and various PK/PD applications (e.g., Phoenix, Monolix, NONMEM, Matlab, Simbiology).
Qualifications

  • PhD in Pharmacology, Engineering, Mathematics, Physics, or related fields.
  • Publication record demonstrating successful application of mathematical modeling techniques is required.
  • Experience with pharmacology modeling, or strong background in math/engineering/physics is preferred.
  • The candidate must possess excellent interpersonal, organizational, oral/written communication and teamwork skills.
  • This position is located in Spring House, PA, and may require 10% travel.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Be seen for the talent you bring to your work. Explore opportunities within the Johnson & Johnson Family of Companies.
Primary Location
United States-Pennsylvania-Spring House-Welsh & McKean Roads
Organization
Janssen Research & Development, LLC (6084)
Job Function
R&D
Requisition ID
2105883964W

Expected salary:

Location: Spring House, PA

Job date: Wed, 07 Apr 2021 03:44:50 GMT


More info

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